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MAC Brain Flow Anesthesia Family

MAC Brain
- better anesthetic agent dosing

For more precise control of depth of anesthesia, we created MAC Brain. A unique tool that visualizes the difference in agent concentration between the lungs and the target organ, the brain. The reliability of the data puts you in control, letting you plan and deliver more efficient dosing of agents with safety and ease.[1] [2] [3] [4] 

MAC Brain is a standard feature on all our Flow Family anesthesia machines.

MAC Brain
- a monitoring tool for general anesthesia

Due to pharmacokinetics, there is a time delay in agent concentration between the end-tidal MAC and the target organ. MAC Brain, available with Flow anaesthesia machines, visualizes the difference to support better dosing and planning of agent delivery.

Potential use areas for MAC Brain

Discussions with early adopters of MAC Brain has identified the following uses:

  • Provides more information when monitoring the depth of anesthesia, especially during induction and emergence.
  • Provides additional information when the patient may be at risk of over or underdosing.

The chart illustrates what early adopters answered when asked about the benefits they experienced with MAC Brain during surgery. [4] 

How MAC Brain works

The image shows the interface of the Flow-i anesthesia machine. The end-tidal MAC and MAC brain are found in the lower left corner of the screen (marked with a green frame). The interface snapshot was taken during induction, when the difference between the two values is often the highest.

MAC Brain is visualized on screen using an algorithm based on basic research and pharmacokinetic models. The option is included in the 4.7 software and is easily brought forward and removed from the menu when needed.

More unique innovations for our anesthesia machines

With our flow anesthesia technology you can easily ensure the perfect flow for each patient, finetuning anaesthesia delivery in real time, breath by breath.

Safe low-flow anesthesia AGC

Automatic Gas Control

O2Guard - active hypoxia prevention


Lung recruitment maneuvers

Lung recruitment

ICU ventilation performance and anesthesia delivery

Ventilation performance

Flow-i anesthesia machine

Flow-i anesthesia machine
- our intelligent model

Flow-i is the intelligent workstation, a highly advanced anesthesia machine offering superior ventilation performance, decision support features, a wider range of settings of flows and pressures, and the innovative AGC option. Flow-i provides safe, personalized and cost-efficient care,also for the most challenging patients. Available in three versions, it’s a dynamic solution, including a heightadjustable model, and a pendant model suspended from the ceiling.

Flow-e anesthesia machine

Flow-e anesthesia machine
- our extended model

Flow-e is the extended, flexible workstation for dynamic anesthesia delivery. Featuring Getinge’s proprietary innovations, the machine ensures safe, personalized care for a wide range of patients. With a larger worktop, more storage space, and generous mounting possibilities for auxiliary equipment, Flow-e can be customized to match your needs and preference in safe treatment for patients.

Flow-c anesthesia machine

Flow-c anesthesia machine
- our compact model

Flow-c is the compact, easy-to-use dynamic workstation, enabling safe and cost-efficient treatment. The compact design is an advantage in a crowded OR with a busy schedule. Despite its small size, it has Flow Family advantages such as ventilation performance to ICU standards, precision agent dosing, hypoxia prevention technologies, an intuitive user interface, and several mounting possibilities.

Do you have questions?


  1. Drews FA, Syroid N, Agutter J, Strayer DL, Westenskow DR. Drug delivery as control task: improving performance in common anesthetic task. Hum Factors 2006;48:85–94.

  2. Ross Kennedy, Margie McKellow, Richard French, Jamie Sleigh. Sevoflurane End-Tidal to Effect-Site Equilibration in Women Determined by Response to Laryngeal Mask Airway Insertion. Anesth Analg 2013;117:786–91

  3. Internal report EVU-197031 - 01 - Flow 4.7 Enhanced Post Market Surveillance Report 2019

  4. Internal report EVU-194160 - User evaluation EPMS Flow 4.7 2019