Applikon AppliFlex ST
Applikon AppliFlex ST
Optimized performance and fast bioreactor setup
Single-use bioreactors provide higher throughput thanks to easy setup and operation. Plus minimal operator handling reduces the ever-present risk of contamination. The Applikon AppliFlex ST has been designed to make your life in the lab easy.
Overview
Box-to-Bench solution for lab-scale cultivation
- No more preparing bioreactors
- Eliminate the risk of cross-contamination
- Perform more experiments in a shorter time with less work
- Improve reproducibility and outcomes of your experiments
Easily scale-up your bioprocess with single-use bioreactors in 500 mL, 3 L and 15 L.
Easily configure your bioreactor to match your application
The Applikon AppliFlex ST is different from other single-use bioreactors. It is a fully customizable stirred tank bioreactor. We use 3D printing technology to create any head plate configuration that is optimal for your bioprocess.
These single-use bioreactors are modeled directly on our world standard autoclavable bioreactors and you can be assured each bioreactor meets similar high standards and quality that you enjoy with our glass bioreactors.
Watch the video to view how the AppliFlex offers the flexibility that you need.
This Applikon bioreactor straight to your lab
Are you interested in the single-use Applikon bioreactor, and would you like to get a virtual sample right now? Try these bioreactors in Augmented Reality*.
Scan the QR code on your desktop with your mobile device or click on the link directly on the mobile device and discover how the AppliFlex would be on your bench.
*View this page on an Augmented Reality (AR) compatible device. Augmented Reality (AR) adds digital elements to the camera of your smartphone, creating the illusion that holographic content is a part of a physical world around you.
Applikon AppliFlex ST 500mL
Discover how this 500 mL single-use bioreactor will look in your lab.
Bring the Applikon AppliFlex ST 500 mL in your lab.
Applikon AppliFlex ST 3 L
Scale up to larger single-use bioreactors for higher productivity.
Explore the Applikon AppliFlex ST 3 L in your lab.
Features & Specifications
From Box-to-Bench
Your bioreactor is ready for operation straight from the box. Take your pre-assembled bioreactor from the box, and get started right away. No laminar flowhood, water supply or drain needed, enabling a smooth and fast workflow.
Save time and costs, execute more runs, and reduce your time-to-market.
Full customizable design
Using 3D printing technology allows for easy optimization of the bioreactor to match your process and application. The headplate can be configured to your unique needs from special ports, sampling lines, connectors, and spargers to addition bottles.
Bring your design to life with a custom Applikon AppliFlex ST.
No cross-contamination
The pre-sterilized bioreactor makes your life in the lab easy. No more assembling and sterilizing before you can start your culture. No more cleaning after the culture is finished. Minimal operator handling reduces the ever-present risk of contamination.
Using single-use sensors allows for a fully closed operation, ensuring sterility in your bioprocess.
Specifications
| Physical characteristics | 500 mL | 3 L |
15 L | ||
| Dimensions ( h x Ø ) | 236 mm x 75 mm | 340 mm x 130 mm | 500 mm x 223 mm | ||
| Weight | 0.2 kg (1 bioreactor) | 0.7 kg (1 bioreactor) | 1,7 kg (1 bioreactor) | ||
| Bottom | Dished bottom | ||||
| Total volume | 575 ml | 3 L | 15 L | ||
| Working volume | 100 – 400 ml | 0.65 – 2.4L | 3 - 12 L | ||
| H/D ratio total volume | 2.0 | ||||
| H/D ratio working volume | 1.33 | ||||
| Impeller type | Marine / Rushton / Anchor / None / Hydrofoil / Helical and more... | Marine | |||
| Impeller diameter | 28 mm | 52 mm | 89 mm | ||
| Sparger type | Pipe with Ø2mm hole / Open pipe / Sparger stone / Jet sparger / Porous sparger and more... | ||||
| Operating conditions |
|||||
| Working temperature | 5 – 45 °C | ||||
| Storage temperature | -80 – 45 °C | ||||
| Design pressure | 0 – 0.5 barg | 0 – 0.1 barg | |||
| Mixing time | ~3 seconds | ||||
| Sterilization | >25 kGy Gamma irradiation | ||||
| Sensors options | Single-use sensors or traditional multi-use sensors | ||||
Applications
The Applikon AppliFlex ST is ideal for the following applications:
- Cell line development, process development and scale up studies
- Batch, fed-batch and perfusion
- Cell and Gene applications (IPC’s, T&NK Cells, and MSc’s)
- Cell culture applications (CHO, HEK, BHK and Sf9)
- Fermentations (S. cerevisiae, K. lactis, B. subtilis and E. coli)
Customized single-use AppliFlex bioreactors
with various impellers and ports
to match bioprocessing needs
Downloads
Related products
Livit Flex
The Livit Flex is the intuitive controller that fits any research and development application. It can be configured as a single or dual control system for single-use and / or multi-use bioreactors. Only one network is needed to monitor and control the data of all your bioprocesses.
Applikon Alcohol Fermentation Monitor
The Applikon Alcohol Fermentation Monitor (AFM) is a robust and user-friendly laboratory parallel fermentation system that allows for accurate comparisons of carbon conversion rates and yields for six simultaneous anaerobic fermentations.
Applikon Micro-Flask
An easy-to-use, and cost-effective technology platform for the rapid handling and growth of large numbers of microbial strains, clonal libraries, mutant banks, and cell lines. This system enables a single person to grow and test thousands of strains simultaneously with a minimum of repetitive handlings.
Applikon my-Control
The my-Control is ideal for small scale cultivations as this controller requires less bench space than other controllers. This advanced system can control single- and multi-use bioreactors from 50 mL (working volume) up to a total volume of 3 L for both cell culture and microbial cultures.
Applikon ez2-Control
The ez2-Control is there to simplify your bioprocess. Its multiple software innovations make it easy to control your bioreactor. The web-interface for the ez2-Control provides a clear overview of the parameters of your bioprocess, putting the attention right where it’s needed.
Applikon Motor Controller
The Motor Controller is a robust and user-friendly device that allows for easy and stable mixing. The Motor Controller can be supplied with 4 different types of brushless stirrer motors that can support mixing in vessels up to 130 L.
Applikon in-Control
The in-Control is a process controller for laboratory scale bioreactors, offering high level control on a small footprint. This modular system allows you to create the most optimal set-up as you can add any extra inputs or outputs. You are in control.
Applikon BioSep
The Applikon BioSep is a unique cell retention device for the process of constant feeding of fresh media and removal of spent media, while retaining a high number of viable cells. It uses high frequency resonant ultrasonic waves to separate cells and thereby automatically removes cell debris, which makes it the perfect solution for continuous bioprocesses.