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GEC Water Cascade Sterilizers

GEC Water Cascade Sterilizers

High-throughput terminal sterilization

GEC Water Cascade Sterilizers are primarily intended for terminal sterilization of large volumes of liquids in sealed glass or plastic containers.


Water Cascade sterilizers deliver sterility of the product in a rapid cycle, yet are gentle enough to protect the integrity and shape of components, products, and packaging. A wide range of sterilization cycles provides application versatility. Water Cascade sterilizers use water as the sterilization media, recirculated by a high-capacity pump. These sterilizers are designed for high throughput, managing large quantities of goods in biopharmaceutical production facilities.

Flexible process design

Program and processing parameters play an important role in the protection of pharmaceutical products and packaging. The GEC Water Cascade Sterilizers provide a versatile line-up of sterilization cycles to meet your products’ unique requirements. Getinge works with you to define the correct processing conditions, and can conduct test runs on your products during evaluation to ensure optimal sterilization outcomes.

Effective process control

Correct pressure and evenly distributed temperature are key to process efficacy while preventing deformation or damage of containers. Temperature and pressure are determined by the liquid being sterilized, fill volume, container material style and type of closure.

During sterilization, water cascades from a perforated tray at the top of the chamber to create a uniform temperature throughout the load during the sterilization phase. Temperature and pressure are independently controlled; by accurately linking pressure adjustments to any change in load temperature, optimal process conditions can be achieved.

Efficient throughput

Throughput is an important concern in production settings where large quantities of liquids in glass or plastic containers must be rapidly processed. GEC Water Cascade Sterilizers utilize a closed loop water system in combination with a high capacity pump that contribute to rapid heating and cooling and an overall short cycle time.

To meet various productivity needs, the GEC Water Cascade Sterilizers are offered in standard chamber sizes ranging from 0,43 m3 up to 16,2 m3. Getinge can support you with custom-made sizes and configurations to meet your specific production and process requirements.

Automated loading solutions

In a busy production environment, transporting products to and from a sterilization chamber is a logistical challenge. Often large, heavy loads must be moved daily to maintain productivity. Yet manual handling is difficult to control according to the validated processes. Getinge supports you with automated, ergonomically friendly solutions for load handling. Conveyor systems and robotic loading play an integral part in maximizing throughput and ensuring process control.

Rack design supports efficacy

Rack and shelf design play a key role in process efficacy and product protection. They must allow adequate and uniform flow of sterilizing media while supporting the product to prevent damage or deformation. Getinge supports you with wide variety of shelving systems, and offers test and prototyping services to assist in the design of shelving for your specific process requirements.

Customer installation

Customer case

Discover more about Getinges automated load handling solutions for terminal sterilization.

Process optimization support

Ensure an optimal sterilization process

We work together with you to develop the optimal cycle for your processing needs. Getinge can help you optimize testing and process development conditions at our process development lab in Getinge, Sweden. A specially designed sterilizer allows for programming of a wide range of sterilization cycles, giving you full control to optimize process parameters. 


Terminal sterilization

GMP regulations require that a product must be terminally sterilized if it doesn’t the quality, safety or efficacy of the packaged product. Our sterilization processes help you meet GMP regulations for all types of large volume and small volume parenteral packaging including ampoules, syringes, cartridges, IV bags, BFS containers, rigid glass, flexible containers, and more.