Applying the DPTE® transfer system to a Glovebox

Safe and leak-free transfer of HPAPI

In a recent project, Flow Sciences was approached by a client that needed a specialized containment enclosure. They needed to ensure the safe and leak-free transfer of highly potent active pharmaceutical ingredients (HPAPI) from one enclosure to another. The client had internal policies in place limiting operators’ 8-hour respiratory exposure, expressed as an 8-hour Time Weighted Average (TWA). That exposure would be less than 500 nanograms per cubic meter air (<500 ng/m3) in the breathing zone.

Creation of a secure glovebox workstation

Flow Sciences’ client was already using Getinge’s polyethylene DPTE® Beta Containers (DPTE® PE Containers) in their facility. Working with what the client already had in place, Flow Sciences designed a high-performance solution that capitalized on that existing, validated resource. The Flow Sciences team created a secure glovebox workstation that incorporated a Getinge DPTE® Alpha Rapid Transfer Port to connect to the client’s existing DPTE® Beta Containers. Once connected, the Alpha and Beta components join together to form a single unit. Tightness is secured by the lip seals of the new assembly which can be opened without breaking sterility or containment.

“Flow Sciences is a solution-based company,” said Ray Ryan, Founder and President of Flow Sciences. “Sometimes we have the solution on our shelves, but most of the time we have to develop a solution to fulfill that industry need.”

Safe method for bidirectional transfer

“The DPTE® transfer system is recognized as the safest method for bidirectional transfer in aseptic or toxic working areas, without breaking containment or sterility,” said Keith Savage, Technical Sales Engineer at Getinge. “We’re pleased to see Flow Sciences’ success using DPTE® transfer systems to meet their clients’ strictest aseptic transfer needs.”

Find out how Flow Sciences designed a high-performance solution for a secure glovebox workstation incorporating a Getinge DPTE® Alpha Rapid Transfer Port to connect to the end-user’s existing DPTE® Beta Containers.

Read the Flow Sciences' Case Study "Integrating a DPTE® transfer system to the Flow Sciences, Inc. Glovebox Workstation".