Select Your Country or Region
COVID-19 Resource Center
multi-use bioreactor washing

Proven process on how to best clean and sterilize multi-use bioreactors


Proven process on how to best clean and sterilize multi-use bioreactors

Proper preparation of a multi-use bioreactor will increase productivity, reproducibility and avoid process interruptions. This requires a thorough cleaning of the vessel and all associated components.

The result: Accurate and repeatable result, minimizing research downtime and decreasing labor cost.

Download the whitepaper

Bioreactor preparation solution

6 important steps in the cleaning and sterilization process

  1. Determine if Repeat  or New Process
  2. Disassembly and Washing Prep
  3. Rack Loading, Washing and Reassembly
  4. Preparation for Sterilization
  5. Sterilization
  6. Return to Service

A programmable labware washer with specialty multi-use bioreactor rack assures thorough cleaning, better reproducibility and reduced labor.

The Solution

The combination of pre-validated washing and sterilization performed in the washer and sterilizer maintain an approved standard for quality control that reduces the chance of human error or deviation from proven process

The white paper provides information on how to reduce labor, increase throughput, minimize downtime and have a clean bioreactor ready for the final sterilization.

Download the white paper here:

Bioreactor Preparation Solutions white paper.png

Applikon bioreactor systems

The Applikon bioreactor system portfolio covers the whole upstream bioprocess, ranging from laboratory scale and pilot plant scale to production scale.

Read more about Applikon bioreactor systems


Getinge’s portfolio of washers meets a broad set of cleaning applications in the Life Science industry, ranging from cGMP cleaning in biopharmaceutical production to the research space. For a variety of laboratory settings Getinge’s laboratory washers provide clean and contamination free glass and labware.

Read more about Decontamination


In the production space Getinge provides sterilizers for components, equipment and tubs as well as terminal sterilization. In Biomedical research and the vivarium, Getinge offers sterilization systems meeting the need for reprocessing of cages and racks. Dedicated laboratory sterilizers provide reliable processes for a variety of applications and lab requirements.

Read more about Sterilization

Related articles

  • Research Laboratories

Top 3 Causes of Cross Contamination in Biosafety Facilities

Cross contamination in BSL-3 and BSL-4 laboratories represents a significant risk to personnel and the surrounding community due to the dangerous agents housed within these facilities. 

Learn more

  • Research Laboratories

An automated bioreactor solution tailored for the next generation of science

At the Delft University of Technology in the Netherlands, professors and PhD students needed a new solution for evolutionary engineering – to improve the study of genetically engineered cells in the pursuit of replacing more petrochemicals with plant-based materials. This called for a robust, flexible, and automated bioreactor setup tailored to meet the specific challenges related to evolution studies.

Read more

  • Research Laboratories

Best Practices for Multi-Use Bioreactor Sterilization

Regardless of whether the bioreactor is being prepared for a same-use application or an entirely different one, all bioreactor components, as well as liquid media, must be made ready through an effective and reproducible process.

Read more

  • Research Laboratories

5 Factors for Safe Material Transfer in BSL-3 and BSL-4 Facilities

BSL-3 and BSL-4 laboratories highlight the fact that if proper protocols are not followed, contamination can cause detrimental results.

Learn more

  • Research Laboratories

The 4 Pillars of Successful Labware Cleaning

Clean labware is a critical component in any laboratory because contaminated labware can lead to false test results and expensive re-testing.

Learn more